Surgery, Gastroenterology and Oncology (SGO)
Latest issue of Surgery, Gastroenterology and Oncology (SGO)
Inflammatory Responses in Liver Transplantation
Successful liver transplantation requires proper mitigation of stress responses. Systemic effects caused by liver cirrhosis, invasive surgery, ischemia-reperfusion injury, rejection, and infection, all of which are relevant to liver transplantation, are mediated by inflammatory factors.
Recently, the detailed mechanisms of inflammation have been elucidated.
Domino Liver Transplantation: Current Status
Domino Liver transplant (DLT) is a strategy to address organ shortage and expand the liver donor pool for liver transplantation. Despite offering some unique technical challenges, DLT appears to be a safe and reasonable option to be considered for selected patients who
would otherwise not benefit from liver transplantation.
Liver Transplantation and Surgery in the Management of Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the second cause of cancer related deaths worldwide constitutes a major global health problem. Although our understanding of the molecular pathogenesis of hepatocellular HCC has improved, detected driver mutations are not yet sufficiently reliable therapeutic targets.
Liver Transplantation During COVID-19 Pandemic: Experience of a Single High-Volume Italian
Center in the Eye of the Storm
The first wave of coronavirus disease 2019 (COVID-19) pandemic accounted for roughly 35,000 deaths in Italy and was mainly concentrated in the industrial north of the country. Despite Italy returned to a partial lockdown during December, the number of people dying in the second wave has now surpassed the toll
recorded in the first.
A Combined Program of Cadaveric and Living-Related Liver Transplantation in a Single Center:
An Experience of 1,000 Operations
Background: The liver transplantation program of Fundeni Clinical Institute reached a milestone (1000 operations performed by the same team in 20 years). It is a program for both adults and children, including cadaveric and living donor liver transplantations. We analyze the indications and results to emphasize the advantages of a combined program.
Biliary Complications Following Orthotopic Liver Transplantation: The Place of Surgical
Reconstruction in the Minimally-Invasive Era
Background: Biliary complications are the more frequent problem following liver transplantation (LT) and have been considered the "Achile's heel" this procedure. The aim of this study was to evaluate the rates of biliary complications after LT, the different therapeutic modalities currently available and their outcomes.
Predictive Factors of Early Mortality after Living Donor Liver Transplantation: A Single Center
Experience of 780 Cases over 16 Years
Introduction: Living-donor liver transplantation (LDLT) is a complex procedure requiring a special perioperative patients care. Despite the improvements in the operative techniques and perioperative care, early postoperative mortality remains a disappointing event. The current
study is conducted to determine the incidence, causes and potential predictive factors of early postoperative mortality after LDLT.
Technical Advancements in Living Donor Liver Transplant
Over the past 2 decades, living donor liver transplantation has become a standard and accepted alternative to deceased donor liver transplantation, especially in countries with poor cadaveric donation rates. Numerous innovations in surgical technique along with improved understanding of post-transplant physiology have led to LDLT having
comparable and sometimes exceeding outcomes of DDLT.
Outflow Reconstruction Techniques in Living Donor Liver Transplantation
Liver transplantation is a therapeutic option for acute and chronic end stage liver diseases and certain hepatic malignant tumors. The growing disparity between the number of liver transplant candidates and the supply of deceased donor organs has led the increase
living donor liver transplantation (LDLT).
Technical Tips in Laparoscopic Donor Right Hepatectomy in Living Donor Liver Transplantation
Although laparoscopic donor right hepatectomy (LDRH) is increasingly performed in adult living donor liver transplantation, most experiences have been reported from a limited number of major transplant centers. This is because LDRH requires high-level surgical skills and a guarantee of donor safety.